Review



growth and differentiation factor-5 (gdf-5)  (ProSpec)


Bioz Verified Symbol ProSpec is a verified supplier
Bioz Manufacturer Symbol ProSpec manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    ProSpec growth and differentiation factor-5 (gdf-5)
    Growth And Differentiation Factor 5 (Gdf 5), supplied by ProSpec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/recombinant+human+gdf+5+protein/pm24474722-48-2-13
    Average 90 stars, based on 1 article reviews
    growth and differentiation factor-5 (gdf-5) - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    other:

    Article Title: Preferential tendon stem cell response to growth factor supplementation.
    Article Snippet: Tendon injuries are increasingly prevalent around the world, accounting for more than 100 000 new clinical cases/year in the USA alone.. Cell-based therapies have been proposed as a therapeutic strategy, with recent data advocating the use of tendon stem cells (TSCs) as a potential cell source with clinical relevance for tendon regeneration.. However, their in vitro expansion is problematic, as they lose their multipotency and change their protein expression profile in culture.



    Similar Products

    growth and differentiation factor-5 (gdf-5)  (ProSpec)
    90
    ProSpec growth and differentiation factor-5 (gdf-5)
    Growth And Differentiation Factor 5 (Gdf 5), supplied by ProSpec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/recombinant+human+gdf+5+protein/pm24474722-48-2-13
    Average 90 stars, based on 1 article reviews
    growth and differentiation factor-5 (gdf-5) - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth/differentiation factor 5 (gdf-5)  (PeproTech)
    90
    PeproTech growth/differentiation factor 5 (gdf-5)
    Growth/Differentiation Factor 5 (Gdf 5), supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/gdf5+growth+factor/pm38734200-72-41-38
    Average 90 stars, based on 1 article reviews
    growth/differentiation factor 5 (gdf-5) - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth and differentiation factor 5 gdf-5  (PeproTech)
    90
    PeproTech growth and differentiation factor 5 gdf-5
    Growth And Differentiation Factor 5 Gdf 5, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/gdf5+growth+factor/pmc11043557-70-23-27
    Average 90 stars, based on 1 article reviews
    growth and differentiation factor 5 gdf-5 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth differentiation factor 5 (gdf-5)  (PeproTech)
    90
    PeproTech growth differentiation factor 5 (gdf-5)
    Growth Differentiation Factor 5 (Gdf 5), supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/gdf5+growth+factor/pm36017070-100-55-67
    Average 90 stars, based on 1 article reviews
    growth differentiation factor 5 (gdf-5) - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth and differentiation factor-5 gdf-5  (PeproTech)
    90
    PeproTech growth and differentiation factor-5 gdf-5
    Growth And Differentiation Factor 5 Gdf 5, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/gdf5+growth+factor/pm35781799-64-16-19
    Average 90 stars, based on 1 article reviews
    growth and differentiation factor-5 gdf-5 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth differentiation factor 5 gdf-5  (PeproTech)
    90
    PeproTech growth differentiation factor 5 gdf-5
    Growth Differentiation Factor 5 Gdf 5, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/gdf5+growth+factor/pmc09137312-102-45-50
    Average 90 stars, based on 1 article reviews
    growth differentiation factor 5 gdf-5 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth differentiation factor (gdf) 5 (gdf5)  (Biopharm GmbH)
    90
    Biopharm GmbH growth differentiation factor (gdf) 5 (gdf5)
    ( A,B ) Neurite length of neurons in E14 rat VM cultures transfected with control siRNA, Smad4 siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid before being cultured with or without 10 ng/ml <t>GDF5</t> for 72 h (*** P <0.001 compared with control; ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; number of repetitions ( n )=3 experiments). All data are presented as mean ± S.E.M. ( C ) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.
    Growth Differentiation Factor (Gdf) 5 (Gdf5), supplied by Biopharm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/recombinant+human+gdf+5/pmc07371012-46-12-18
    Average 90 stars, based on 1 article reviews
    growth differentiation factor (gdf) 5 (gdf5) - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    recombinant human growth and differentiation factor-5 gdf-5  (Biopharm GmbH)
    90
    Biopharm GmbH recombinant human growth and differentiation factor-5 gdf-5
    ( A,B ) Neurite length of neurons in E14 rat VM cultures transfected with control siRNA, Smad4 siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid before being cultured with or without 10 ng/ml <t>GDF5</t> for 72 h (*** P <0.001 compared with control; ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; number of repetitions ( n )=3 experiments). All data are presented as mean ± S.E.M. ( C ) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.
    Recombinant Human Growth And Differentiation Factor 5 Gdf 5, supplied by Biopharm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/recombinant+human+gdf+5/pm23680368-36-4-7
    Average 90 stars, based on 1 article reviews
    recombinant human growth and differentiation factor-5 gdf-5 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    growth and differentiation factor (gdf)-5  (Forschungszentrum gmbh)
    90
    Forschungszentrum gmbh growth and differentiation factor (gdf)-5
    ( A,B ) Neurite length of neurons in E14 rat VM cultures transfected with control siRNA, Smad4 siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid before being cultured with or without 10 ng/ml <t>GDF5</t> for 72 h (*** P <0.001 compared with control; ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; number of repetitions ( n )=3 experiments). All data are presented as mean ± S.E.M. ( C ) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.
    Growth And Differentiation Factor (Gdf) 5, supplied by Forschungszentrum gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/growth+and+differentiation+factor-5+(gdf-5)/growth+and+differentiation+factor++gdf++5/10__1007_slash_s00423___010___0676___4-866-28-16
    Average 90 stars, based on 1 article reviews
    growth and differentiation factor (gdf)-5 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    ( A,B ) Neurite length of neurons in E14 rat VM cultures transfected with control siRNA, Smad4 siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid before being cultured with or without 10 ng/ml GDF5 for 72 h (*** P <0.001 compared with control; ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; number of repetitions ( n )=3 experiments). All data are presented as mean ± S.E.M. ( C ) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.

    Journal: Neuronal Signaling

    Article Title: Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson’s disease

    doi: 10.1042/NS20170181

    Figure Lengend Snippet: ( A,B ) Neurite length of neurons in E14 rat VM cultures transfected with control siRNA, Smad4 siRNA or Smad1 siRNA or Smad5 siRNA and a GFP-expressing plasmid before being cultured with or without 10 ng/ml GDF5 for 72 h (*** P <0.001 compared with control; ANOVA with post-hoc Tukey’s test; 40 cells for each group per experiment; number of repetitions ( n )=3 experiments). All data are presented as mean ± S.E.M. ( C ) Representative photomicrographs of GFP+ neurons in cultures of E14 rat VM. Scale bar as indicated.

    Article Snippet: Where indicated, cells were treated daily with 10 or 200 ng/ml of growth differentiation factor (GDF) 5 (GDF5) (Biopharm GmbH), which are maximal saturating concentrations in primary and SH-SY5Y cell cultures respectively [ , ].

    Techniques: Transfection, Control, Expressing, Plasmid Preparation, Cell Culture

    ( A ) Densitometric analysis of p-Smad1/5 in SH-SY5Y cells treated with 200 ng/ml of GDF5 for 0 (control), 5, 30 and 60 min. ( B ) Neurite length of GDF5-treated (200 ng/ml daily for 72 h) SH-SY5Y cells at 72 h. ( C–F ) p-Smad1/5 levels as determined by ( C, D ) Western blots or ( E, F ) immunocytochemistry in SH-SY5Y cells 24 h after transfection with control miRNA or miR-181a inhibitor. Total Smad1/5 was used as a loading control. ( G ) Neurite length, ( H ) neurite branching and ( I ) representative photomicrographs of miR-181a inhibitor or control miRNA transfected SH-SY5Y cells at 72 h (* P <0.05, ** P <0.01, *** P <0.001 compared with control; t test; 40 cells for each group per experiment; n =3 experiments). All data are presented as mean ± S.E.M. Scale bar as indicated.

    Journal: Neuronal Signaling

    Article Title: Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson’s disease

    doi: 10.1042/NS20170181

    Figure Lengend Snippet: ( A ) Densitometric analysis of p-Smad1/5 in SH-SY5Y cells treated with 200 ng/ml of GDF5 for 0 (control), 5, 30 and 60 min. ( B ) Neurite length of GDF5-treated (200 ng/ml daily for 72 h) SH-SY5Y cells at 72 h. ( C–F ) p-Smad1/5 levels as determined by ( C, D ) Western blots or ( E, F ) immunocytochemistry in SH-SY5Y cells 24 h after transfection with control miRNA or miR-181a inhibitor. Total Smad1/5 was used as a loading control. ( G ) Neurite length, ( H ) neurite branching and ( I ) representative photomicrographs of miR-181a inhibitor or control miRNA transfected SH-SY5Y cells at 72 h (* P <0.05, ** P <0.01, *** P <0.001 compared with control; t test; 40 cells for each group per experiment; n =3 experiments). All data are presented as mean ± S.E.M. Scale bar as indicated.

    Article Snippet: Where indicated, cells were treated daily with 10 or 200 ng/ml of growth differentiation factor (GDF) 5 (GDF5) (Biopharm GmbH), which are maximal saturating concentrations in primary and SH-SY5Y cell cultures respectively [ , ].

    Techniques: Control, Western Blot, Immunocytochemistry, Transfection